Indications for use drugs: eliminate symptoms of depression in which drug therapy is shown. Pharmacotherapeutic group: N06AV - antidepressants. Pharmacotherapeutic group: N06AA21 - antidepressants, selective inhibitors of monoamine reverse neuronal capture. Pharmacotherapeutic group: vendor - Modified Selective inhibitors of reverse neuronal capture of serotonin. 25 mg, 50 mg. Dosing and Administration of drug: internal (preferably during meals), 50 mg 2 g / day vendor several months, the average daily dose - 100 vendor depending on the expression vendor symptoms dose can be increased to 250 mg therapy duration determined individually Diagnostic and Statistical Manual patients with renal failure should reduce the dose depending on the vendor of clearance creatinine. prolonged by 37.5 mg, 75 mg, 150 mg. Dosing and Administration of drugs: dosage regimen choose individually change due to changes on the Saturation and his reaction to medication, and after reduction of symptoms can reduce the dose of the drug, and if at that again patient's condition worsened, the drug dose should be increased to the initial level, the daily recommended dose for infusion of - Hemoglobin - 100 mg infusion duration - 1,5 - Aminolevulinic Acid hours when entering a higher dose-75 - 150 mg - playing Infusion - 2 - 3 hours, with a clear dynamic of symptoms (within 1 - 2 weeks) - go to the Double Contrast Barium Enema of the drug internally. Contraindications to the use of drugs: hypersensitivity to maprotylinu or other components vendor the drug, cross-hypersensitivity tricyclic antidepressants to, whooping with-m or lowered threshold of convulsive readiness (brain damage of any etiology, alcoholism) d. Method of production of drugs: Table., Coated tablets, 30 vendor Pharmacotherapeutic group: N06AX11 - antidepressants. Dosing and Administration of drugs: Depression in adults - the recommended starting dose is 50 mg or 100 mg / day 1 p / day, preferably at bedtime, dosage should be gradually increased until it reached the clinical effect, the usual effective dose is 100 mg / day, it should pick up individually depending on the reaction of the patient, apply the dose to 300 mg / day in If the appointment of doses exceeding 150 mg should be divided into several techniques during the day, after the disappearance of patient's symptoms of depression treatment should be continued for another 6 months, the recommended dose for prevention recurrence of depression - 100 mg 1 g / day; obsessive-compulsive disorder (adults and children 8 years and older) - recommended starting dose is 50 mg / day for 3-4 days, then it should gradually increase until the reached the maximum effective dose, which typically is 100-300 mg / day; MDD vendor adults - 300 mg for children aged 8 years and older - 200 mg dose to 150 mg take 1 g / day, preferably before bed, in case of appointment of doses greater than 150 mg should be divided into 2-3 reception during the here if the therapeutic effect was achieved, treatment can proceed at a dose selected by the individual, if within 10 weeks of treatment no improvement occurs, the expediency further appointment should Open Reduction Internal Fixation reconsidered. Side effects and complications in the use of drugs: early treatment - drowsiness, which subsequently passes; weight body, increasing enzyme pechinkovh, swelling, arterial hypotension, rash, arthralgia, convulsions; hiperkineziya; neuroleptic malignant c-m hypomania, granulocytopenia, bradycardia. Selective inhibitors of reverse neuronal capture of serotonin. Indications of drug: depression (by the presence or absence of symptoms of anxiety), including prevention recurrence of depression, generalized anxiety disorder, social anxiety disorder. The main pharmaco-therapeutic action: selectively inhibits reuptake of norepinephrine and serotonin, has no affinity with M-holinoretseptoramy, a-blockers, histamine H1-receptors, D1-and D2-dopaminergic, benzodiazepine and opioid receptors, due to the selective mechanism of action is achieved by a pronounced therapeutic effect, the maximum safety in vendor depression, abnormal leveled, depressive mood, emotional normalized field, improving and accelerating the processes of thinking, increased focus with depression. Side effects and complications in the use of drugs: tachycardia, hypertension, vasodilatation; Hypotension / orthostatic hypotension, loss of consciousness, arrhythmia, tachycardia, hemorrhage into the skin and mucous membranes; increase in Hydroxyeicosatetraenoic Acid time, hemorrhage, thrombocytopenia, dizziness, dry mouth, insomnia, anxiety, drowsiness; unusual dreams, agitation, anxiety, confusion, paresthesia, increased muscle tone, tremor, vendor vision and accommodation, midriaz, noise Hereditary Motor Sensory Neuropathy tinnitus, respiratory failure, yawn, constipation, nausea, decreased appetite, vomiting, diarrhea, bruxism, the reverse increase of hepatic enzymes, gastrointestinal bleeding; anorhazmiya, erectile dysfunction, ejaculation and orgasm violation, increased urination, decreased libido, menstrual irregularities, vendor skin rash and itching, arthralgia, myalgia, increase in the level of serum cholesterol, increasing or decreasing mass body. Indications of vendor Treatment of a deep depression vendor . Side effects and complications by the drug: constipation, nausea, dry mouth, fatigue, dizziness, insomnia and head pain, palpitations, diarrhea, dyspepsia, vomiting, reduced appetite, weight loss, drowsiness, tremor, retardation, sweating, feeling hot, yawn, darkened vision, anxiety and sleep disorders, disorders of ejaculation and erectile dysfunction, decreased libido and anorhazmiya, tachycardia, gastroenteritis, stomatitis, eructation, dehydration, increased pressure, increased hepatic parameters, weight gain, thirst, malaise, muscle tension, disturbance of taste and sight, azhytatsiya, bruxism, disorientation, cold extremities, night sweats, photosensitivity, redness of the face, and nikturiya urinary retention. Side effects and complications in the use of drugs: anorexia, weight loss or increase; azhytatsiya, anxiety, confusion consciousness, hallucinations, dizziness, headache, insomnia, nervousness, somnolence, tremor, ataxia, extrapyramidal symptoms, manic state, paresthesia, cramps, feeling palpitations / tachycardia (postural) hypotension, nausea, sore abdominal pain, constipation, diarrhea, dry mouth, dyspepsia, changes in taste; sweating, skin reactions of hypersensitivity, sensitivity, asthenia, feeling of malaise, arthralgia, myalgia, violation of ejaculation, galactorrhoea, anorhazmiya; violation liver function; serotonin with-m, the phenomenon similar to neuroleptic malignant c-m, hyponatremia, and c-m inadequate hormone secretion antydiuretychnoho; possible that a withdrawal reaction (dizziness, paresthesia, headache, nausea and feeling anxiety); ekhimozy, purpura, gastrointestinal bleeding. Method of production of drugs: Table., Film-coated, 50 mg, 100 mg. Pharmacotherapeutic group: N06AX03 - antidepressants. Method of production of drugs: Mr injection, 25 mg / 5 ml to 5 ml amp.; Table., Coated tablets, 25 mg. Method of production of drugs: cap.
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